There are three forms of phenylalanine, L- phenylalanine (natural form), D-phenylalanine (artificial version) and DLPA (a combination of both L and D types). The first is present in brain, while the latter two cannot be synthesized by the body. Hence, they need to be supplemented externally via our diet. Nutritional supplements containing this amino acid are advocated in case of deficiency symptoms. Nevertheless, the safety of phenylalanine supplements should be analyzed thoroughly before ingesting them for health purpose. The following info explains about the probable side effects of phenylalanine.
Phenylalanine side effects are pronounced in people who have a medical history of phenylketonuria (PKU), a metabolic disorder characterized by lack of enzyme for processing phenylalanine. Thus, phenylalanine is accumulated in the body.
In children affected with PKU and ADHD, providing a low dose of external phenylalanine or foods containing aspartame is linked with life-threatening medical complications. Whereas, adult patients may experience mild to severe effects, based on the intake dose. Learn more on aspartame side effects.
In patients with high blood pressure, phenylalanine exacerbates the existing condition by further elevating blood pressure. Thus, hypertension patients should avoid taking this amino acid supplement.
Coming to phenylalanine dose, 500 mg of L-phenylalanine per day is safe, while the daily dose of DLPA ranges from 75-1,500 mg. Taking excess dose increases the risks for manifesting phenylalanine side effects.
Phenylalanine directly affects the neural tissues and is strictly not recommended for pregnant women and lactating mothers. Also, patients with underlying medical problems should refrain from taking this amino acid supplement.
Increased concentration of DLPA or prolonged intake of the same is associated with headache, nauseated feeling and heartburn. The higher the concentration, the more severe will be phenylalanine side effects. It can even lead to cellular death.
Phenylalanine is shown to have drug interaction effects. Thus, those who are currently on hypertension drugs and antidepressants (especially those containing monoamine oxidase inhibitors) should not take phenylalanine. Also, it should not be taken in conjunction with high protein diet.
Patients with schizophrenia, hyperthyroidism and cancer should take doctor's approval before taking phenylalanine supplement. Failure to do so may result in unusual phenylalanine side effects.
Intake of high phenylalanine increases the risks for behavioral and mental problems. Regarding overdose with this neurotoxin, there are few incidences of irreversible damage in the brain tissues and ultimately, death of patients.
Overdose of phenylalanine results in toxicity symptoms, and may result in nervous breakdown. The lethal dose of phenylalanine differs according to the supplement type.
Phenylalanine side effects are pronounced in people who have a medical history of phenylketonuria (PKU), a metabolic disorder characterized by lack of enzyme for processing phenylalanine. Thus, phenylalanine is accumulated in the body.
In children affected with PKU and ADHD, providing a low dose of external phenylalanine or foods containing aspartame is linked with life-threatening medical complications. Whereas, adult patients may experience mild to severe effects, based on the intake dose. Learn more on aspartame side effects.
In patients with high blood pressure, phenylalanine exacerbates the existing condition by further elevating blood pressure. Thus, hypertension patients should avoid taking this amino acid supplement.
Coming to phenylalanine dose, 500 mg of L-phenylalanine per day is safe, while the daily dose of DLPA ranges from 75-1,500 mg. Taking excess dose increases the risks for manifesting phenylalanine side effects.
Phenylalanine directly affects the neural tissues and is strictly not recommended for pregnant women and lactating mothers. Also, patients with underlying medical problems should refrain from taking this amino acid supplement.
Increased concentration of DLPA or prolonged intake of the same is associated with headache, nauseated feeling and heartburn. The higher the concentration, the more severe will be phenylalanine side effects. It can even lead to cellular death.
Phenylalanine is shown to have drug interaction effects. Thus, those who are currently on hypertension drugs and antidepressants (especially those containing monoamine oxidase inhibitors) should not take phenylalanine. Also, it should not be taken in conjunction with high protein diet.
Patients with schizophrenia, hyperthyroidism and cancer should take doctor's approval before taking phenylalanine supplement. Failure to do so may result in unusual phenylalanine side effects.
Intake of high phenylalanine increases the risks for behavioral and mental problems. Regarding overdose with this neurotoxin, there are few incidences of irreversible damage in the brain tissues and ultimately, death of patients.
Overdose of phenylalanine results in toxicity symptoms, and may result in nervous breakdown. The lethal dose of phenylalanine differs according to the supplement type.
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